Drugs of the future will be easier and faster to make, thanks to mRNA – after researchers work out a few remaining kinks

Mon, 5 Feb 2024 19:23:49 +1100

Andrew Pam <xanni [at] glasswings.com.au>

Andrew Pam

"Vaccines have been reliably and affordably protecting people from diseases
worldwide for centuries. Until the COVID-19 pandemic, however, vaccine
development was still a long and idiosyncratic process. Traditionally,
researchers had to tailor manufacturing processes and facilities for each
vaccine candidate, and the scientific knowledge gained from one vaccine was
often not directly transferable to another.

But the COVID-19 mRNA vaccines brought a new approach to vaccine development
that has far-reaching implications for how researchers make drugs to treat many
other diseases.

I am a biochemist, and my lab at UMass Chan Medical School focuses on
developing better ways to use mRNA as a drug. Although there are many
possibilities for what researchers can use mRNA to treat, some important
limitations remain. Better understanding how mRNA-based drugs interact with the
immune system and how they are degraded in human cells can help lead to safe,
durable and effective treatments for a wide range of diseases."

       *** Xanni ***
mailto:xanni@xanadu.net               Andrew Pam
http://xanadu.com.au/                 Chief Scientist, Xanadu
https://glasswings.com.au/            Partner, Glass Wings
https://sericyb.com.au/               Manager, Serious Cybernetics

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